Supplements Dietary Supplements Is Bergamot Good for You? A pharmacist explains the health benefits of this aromatic citrus fruit and how to use it. By Megan Nunn, PharmD Updated on March 06, 2024 Medically reviewed by Elizabeth Barnes, RDN Print Table of Contents View All Table of Contents What Is Bergamot? How It Smells How It's Used Health Benefits Is It Good for You? Bergamot (Citrus bergamia) is a yellow-green citrus fruit that grows on the coast of southern Italy. A fruit that's part of the heart-healthy Mediterranean diet, bergamot has been studied for conditions ranging from anxiety to high cholesterol. The following article covers the benefits of bergamot, its nutrition, and other considerations. Fruits of the bergamot orange (Citrus bergamia). Mario Krpan / Getty Images What Is Bergamot? Bergamot has traditionally been used to flavor food and to make scented deodorants and perfumes. It's also been used historically for conditions like: Wound care Bacterial infections Toothaches Malaria More recently, it's been investigated for its effects on heart protection and mental health. Notable components (parts) of bergamot include the following: Flavonoids, nutrients with antioxidant properties Limonene and linalool, which give bergamot its fragrance, have been studied for their positive impact on anxiety and depression Linalyl acetate, which has antibiotic effects Coumarins, which can cause sensitivity to sunlight What Does Bergamot Smell Like? Bergamot has a spicy citrus scent. It's responsible for the distinct flavor of Earl Grey tea and has a bitter taste similar to grapefruit. How Do You Use Bergamot? Depending on its formulation, bergamot can be inhaled, taken by mouth, or applied to your skin or hair. It's available in the following forms: Essential oil, a highly concentrated product typically diluted in a carrier oil like olive oil to reduce toxicity. Essential oils may be applied to the skin or inhaled via a diffuser, often for 15 to 30 minutes daily. Essential oils are not to be taken by mouth. Extract, high in flavonoid content, and either applied to the skin or taken by mouth Polyphenolic fraction, available in tablet form and typically taken at 500 milligrams (mg) twice a day Juice, which has antioxidants and can help with signs of aging effects, according to laboratory studies For best results, follow the manufacturer's directions and suggested dosage. Discuss bergamot with a healthcare provider before using it to optimize safety. Health Benefits of Bergamot Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian nutritionist (RD or RDN), pharmacist, or healthcare provider. No supplement is intended to treat, cure, or prevent disease. Bergamot essential oil has been studied in humans for the following conditions: Anxiety Depression High blood pressure (hypertension) High cholesterol Type 2 diabetes Sleep Pain Psoriasis Fatty liver disease Abdominal fat Metabolic syndrome (a combination of conditions that together can lead to heart disease, stroke, and type 2 diabetes) Weight loss However, most of the research focuses on the role of bergamot in heart protection and mental health. Here's what you need to know about bergamot's benefits. May Lower High Cholesterol and Lipids High cholesterol is a risk factor for heart disease. Keeping cholesterol levels at goal is a crucial way to protect the heart. Bergamot is one of the most effective nutraceuticals (food-based products) for lowering cholesterol. It's thought to act on the HMG-CoA reductase pathway like statins (prescription cholesterol medications). In adults, taking 500 to 100 mg per day of bergamot extract or bergamot flavonoids by mouth for up to 180 days improved the lipid panel by lowering the following: Total cholesterol by up to 31% Triglycerides by up to 39% Low-density lipoprotein (LDL) cholesterol ("bad cholesterol") by up to 40% For comparison, high-dose statin therapy aims to lower LDL cholesterol by about 50%. Bergamot also increased high-density lipoprotein (HDL) cholesterol ("good cholesterol"), lowering heart disease risk. Bergamot's effects on cholesterol are typically seen after 30 days of use. Remember that more large-scale clinical trials are still needed because most studies have used small sample sizes. May Reduce Anxiety and Depression In theory, bergamot essential oil has sedative properties similar to Valium (diazepam). Animal studies have shown that it lowers the body's stress response by blocking the hypothalamus-pituitary-adrenocortical (HPA) axis. Recent clinical trials have studied the effects of bergamot essential oil, mostly in females. But so far, there's only limited evidence to recommend bergamot aromatherapy for either anxiety or depression. One study of 41 healthy college-aged females showed that inhaling bergamot vapor (essential oil mixed with water in a diffuser) for 10 minutes improved mood. It also decreased fatigue and levels of the stress hormone cortisol. It's unknown if other groups, including those with chronic health conditions, would have similar responses. Another study of 57 adults (primarily females) at a mental health facility concluded that 15 minutes of bergamot aromatherapy improved positive feelings. A small study of 60 females who were postpartum (after giving birth) showed that inhaled bergamot helped with depression. The participants breathed in vaporized essential oil (mixed with water in a diffuser) as an aromatherapy treatment for 15 minutes daily. More large-scale studies are needed to determine bergamot's effects on mental health. And since most of the existing research comes from females, clinical trials in males are also needed. May Help Sleep Bergamot essential oil is commonly used as aromatherapy for insomnia (difficulty falling or staying asleep). It causes drowsiness by activating the parasympathetic nervous system, which helps the body relax. Bergamot essential oil improved the quality and duration of sleep and morning alertness, according to a small study of 48 people. Keep in mind that about 90% of the people studied did not have trouble sleeping at baseline, so results may not be the same for people with sleep disorders. A combination product containing essential oils of bergamot, lavender, and ylang-ylang improved sleep quality in people hospitalized in a cardiac unit. The product was kept on cotton balls by their bedsides, not applied to the skin. These results also come from a small study of 42 adults. Remember that we can't know for sure what effect, if any, bergamot had since a combination of oils was used. Is Bergamot Good for Me? Bergamot is a safe choice for many people because it has a low risk of side effects. That said, there are some precautions to be aware of if you use it. They include: Avoid bergamot if you're allergic to it or its components (parts). Seek immediate medical attention if you have a severe allergic reaction (itching, hives, shortness of breath). Bergamot essential oil can cause sunburns or skin damage if applied to your skin. If you use it this way, wait at least 12 hours before exposure to the sun. Be careful when using bergamot while pregnant, nursing, or for children. There's not enough data to know if it's safe for these populations. Essential oils, in particular, may affect hormone levels. Also, be careful when using bergamot with medications like statins for cholesterol. Studies show that bergamot can enhance the effects of statins but may also increase the risk of side effects like muscle pain. Case reports suggest that very high doses of bergamot tea may be associated with muscle cramps and blurry vision. Dietary Supplements In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. When choosing a supplement, look for third-party tested products and consult a healthcare provider, RD or RDN, or pharmacist. Summary Bergamot is a citrus fruit native to Italy used in food flavoring and cosmetics. It has also been studied for various health conditions. Bergamot has lowered cholesterol and triglyceride levels and enhanced the effects of prescription statin drugs. In addition, limited research suggests bergamot may have benefits for anxiety, depression, and sleep. Since the existing trials are small, more large-scale clinical trials are needed to verify bergamot's effects. Bergamot can be inhaled, taken by mouth, or applied to the skin. Note that essential oils are associated with risks like sensitivity to sunlight. Before adding bergamot or any other supplement, discuss the risks and benefits with your healthcare provider. 29 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Adorisio S, Muscari I, Fierabracci A, et al. Biological effects of bergamot and its potential therapeutic use as an anti-inflammatory, antioxidant, and anticancer agent. Pharm Biol. 2023;61(1):639-646. doi:10.1080/13880209.2023.2197010 Rondanelli M, Giacosa A, Morazzoni P, et al. MediterrAsian diet products that could raise HDL-cholesterol: A systematic review. Biomed Res Int. 2016;2016:2025687. doi:10.1155/2016/2025687 Han, X., Gibson, J., Eggett, D. L., et al. Bergamot (Citrus bergamia) essential oil inhalation improves positive feelings in the waiting room of a mental health treatment center: a pilot study. Phytother. Res., 2017;31: 812–816. doi: 10.1002/ptr.5806. Lipert A, Szadkowska I, Matusiak-Wieczorek E, et al. The effect of herbal supplements on blood pressure: Systematic review and meta-analysis. Antioxidants (Basel). 2022;11(8):1419. Published 2022 Jul 22. doi:10.3390/antiox11081419 Ogueta IA, Brared Christensson J, Giménez-Arnau E, et al. Limonene and linalool hydroperoxides review: Pros and cons for routine patch testing. Contact Dermatitis. 2022;87(1):1-12. doi:10.1111/cod.14064 McDonnell B, Newcomb P. Trial of essential oils to improve sleep for patients in cardiac rehabilitation. J Altern Complement Med. 2019;25(12):1193-1199. doi:10.1089/acm.2019.0222 Scuteri D, Hamamura K, Sakurada T, et al. Efficacy of essential oils in pain: A systematic review and meta-analysis of preclinical evidence. Front Pharmacol. 2021;12:640128. Published 2021 Mar 1. doi:10.3389/fphar.2021.640128 Rondanelli M, Peroni G, Riva A, et al. Bergamot phytosome improved visceral fat and plasma lipid profiles in overweight and obese class I subject with mild hypercholesterolemia: A randomized placebo controlled trial. Phytother Res. 2021;35(4):2045-2056. doi:10.1002/ptr.6950 Farrar AJ, Farrar FC. Clinical aromatherapy. Nurs Clin North Am. 2020;55(4):489-504. doi:10.1016/j.cnur.2020.06.015 Orchard A, van Vuuren SF. Carrier oils in dermatology. Arch Dermatol Res. 2019;311(9):653-672. doi:10.1007/s00403-019-01951-8 Perna S, Spadaccini D, Botteri L, et al. Efficacy of bergamot: From anti-inflammatory and anti-oxidative mechanisms to clinical applications as preventive agent for cardiovascular morbidity, skin diseases, and mood alterations. Food Sci Nutr. 2019;7(2):369-384. Published 2019 Jan 25. doi:10.1002/fsn3.903 Da Pozzo E, De Leo M, Faraone I, et al. Antioxidant and antisenescence effects of bergamot juice. Oxid Med Cell Longev. 2018;2018:9395804. Published 2018 Jul 12. doi:10.1155/2018/9395804 Chen ML, Chen YE, Lee HF. The effect of bergamot essential oil aromatherapy on improving depressive mood and sleep quality in postpartum women: A randomized controlled trial. J Nurs Res. 2022;30(2):e201. doi:10.1097/jnr.0000000000000459 Pierdomenico M, Cicero AFG, Veronesi M, et al. Effect of Citrus bergamia extract on lipid profile: A combined in vitro and human study. Phytother Res. 2023;37(9):4185-4195. doi:10.1002/ptr.7897 Mollace V, Scicchitano M, Paone S, et al. Hypoglycemic and hypolipemic effects of a new lecithin formulation of bergamot polyphenolic fraction: A double blind, randomized, placebo- controlled study. Endocr Metab Immune Disord Drug Targets. 2019;19(2):136-143. doi:10.2174/1871530319666181203151513 Wakui N, Togawa C, Ichikawa K, et al. Relieving psychological stress and improving sleep quality by bergamot essential oil use before bedtime and upon awakening: A randomized crossover trial. Complement Ther Med. 2023;77:102976. doi:10.1016/j.ctim.2023.102976 Ferro Y, Maurotti S, Mazza E, et al. Citrus bergamia and cynara cardunculus reduce serum uric acid in individuals with non-alcoholic fatty liver disease. Medicina (Kaunas). 2022;58(12):1728. Published 2022 Nov 26. doi:10.3390/medicina58121728 Capomolla AS, Janda E, Paone S, et al. Atherogenic index reduction and weight loss in metabolic syndrome patients treated with a novel pectin-enriched formulation of bergamot polyphenols. Nutrients. 2019;11(6):1271. Published 2019 Jun 4. doi:10.3390/nu11061271 Jung E, Kong SY, Ro YS, et al. Serum cholesterol levels and risk of cardiovascular death: a systematic review and a dose-response meta-analysis of prospective cohort studies. Int J Environ Res Public Health. 2022;19(14):8272. Published 2022 Jul 6. doi:10.3390/ijerph19148272 Osadnik T, Goławski M, Lewandowski P, et al. A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. Pharmacol Res. 2022;183:106402. doi:10.1016/j.phrs.2022.106402 Lamiquiz-Moneo I, Giné-González J, Alisente S, et al. Effect of bergamot on lipid profile in humans: A systematic review. Crit Rev Food Sci Nutr. 2020;60(18):3133-3143. doi:10.1080/10408398.2019.1677554 Ridker PM, Mora S, Rose L; JUPITER Trial Study Group. Percent reduction in LDL cholesterol following high-intensity statin therapy: potential implications for guidelines and for the prescription of emerging lipid-lowering agents. Eur Heart J. 2016;37(17):1373-1379. doi:10.1093/eurheartj/ehw046 Nauman MC, Johnson JJ. Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers. Integr Food Nutr Metab. 2019;6(2):10.15761/IFNM.1000249. doi:10.15761/IFNM.1000249 Sadeghi-Dehsahraei H, Esmaeili Gouvarchin Ghaleh H, Mirnejad R, et al. The effect of bergamot (KoksalGarry) supplementation on lipid profiles: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2022;36(12):4409-4424. doi:10.1002/ptr.7647 Saiyudthong S, Mekseepralard C. Effect of inhaling bergamot oil on depression-related behaviors in chronic stressed rats. J Med Assoc Thai. 2015;98 Suppl 9:S152-S159. Watanabe E, Kuchta K, Kimura M, et al. Effects of bergamot ( Citrus bergamia (Risso) Wright & Arn.) essential oil aromatherapy on mood states, parasympathetic nervous system activity, and salivary cortisol levels in 41 healthy females. Forsch Komplementmed. 2015;22(1):43-49. doi:10.1159/000380989 Ramsey JT, Shropshire BC, Nagy TR, et al. Essential oils and health. Yale J Biol Med. 2020;93(2):291-305. Published 2020 Jun 29. Zhang X, Guo J, Li J, Chen C, Su G. Pharmacokinetics and pharmacodynamic interaction of bergamottin with atorvastatin in rats. Xenobiotica. 2022;52(5):463-467. doi:10.1080/00498254.2022.2090301 Finsterer J. Earl Grey tea intoxication. Lancet. 2002;359(9316):1484. doi:10.1016/S0140-6736(02)08436-2 By Megan Nunn, PharmD Nunn is a community pharmacist in Tennessee with 12 years of experience in medication counseling and immunization. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit