We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation. Learn more. Nutrition Products & Services The 9 Best Supplements for Heart Health, According to a Dietitian These supplements can help boost your heart health by positively affecting your blood pressure and blood cholesterol By Tamar Kane, MS, RD Updated on April 14, 2024 Medically reviewed by Erika Prouty, PharmD Fact checked by Rich Scherr Print Verywell Health / Brian Kopinski Heart disease is the No. 1 killer for men and women, and according to the Centers for Disease Control and Prevention (CDC), about half of American adults have at least one of three key risk factors for heart disease (high blood pressure, high blood cholesterol, and smoking). Thankfully, many lifestyle changes can benefit heart health, including eating a healthy diet, exercising, and not smoking. According to cardiology dietitian Michelle Routhenstein, MS, RD, CDE, CDN, it's important to remember that, when it comes to heart health, supplements can't override your nutrition and lifestyle. However, if lifestyle changes aren't enough to improve heart health and lower your risk factors for heart disease, a healthcare professional may advise taking medication or a heart health supplement—some common supplements include omega-3s, fiber, magnesium, folate, and coenzyme Q10. Of course, which one you take depends on your individual health situation and whether you're targeting your cholesterol, blood pressure, or another area of concern, which is why we've separated out our picks based on what you're looking at. Before taking a heart health supplement, it’s important to check with a healthcare provider, especially if you take any medication. Almost all of these heart health supplements can interfere with medications you may be on for heart health, like blood thinners, statins, or other medications. Our team of registered dietitians reviews and evaluates every single supplement we recommend according to our dietary supplement methodology. From there, a registered dietitian on our Medical Expert Board reviews each article for scientific accuracy. Always speak with a healthcare professional before adding a supplement to your routine to ensure that the supplement is appropriate for your individual needs and which dosage to take. Our Top Picks for Cholesterol Best Omega 3: Nordic Naturals Ultimate Omega Softgels Best Vegan Omega-3: Ritual Omega-3 DHA EPA Best Fiber Supplement: Yerba Prima Psyllium Husks Powder Best Garlic Supplement: Swanson Odor-Controlled Garlic Best Berberine: Thorne Berberine 1,000 mg Our Top Picks for Blood Pressure Best Coenzyme Q10: GNC CoQ-10, 100 mg Best Magnesium Supplement: Pure Encapsulations Magnesium Best Folate: Doctor’s Best Fully Active Folate Best L-Arginine: NOW Double Strength L-Arginine Are Heart Health Supplements Beneficial? The answer varies depending on many factors, but these groups of people in particular might benefit from a supplement for heart health. Those with high blood pressure: High blood pressure can damage your arteries and decrease blood flow to your heart and brain, increasing your risk of heart disease and stroke. Research shows that some supplements, including omega-3s, CoQ10, magnesium, and berberine, may help lower blood pressure. However, these should not replace any medication you take, and we recommend first speaking with a healthcare provider before starting a supplement, especially if you are on any medication. Those with high cholesterol: Too much LDL cholesterol, or “bad” cholesterol, can increase your risk of heart disease and stroke. If you have high levels of LDL cholesterol, an omega-3 or fiber supplement may be beneficial. Those with elevated triglycerides (fat in the blood): High blood levels of triglycerides can increase the risk of heart attack or stroke. If you have high levels of triglycerides (over 150 mg/dl), fish oil can help lower your levels. Consuming 2-4 grams of omega-3 fats EPA+DHA or EPA per day has been shown to improve triglyceride levels. However, it is important to note that some research suggests above one gram of fish oil per day in supplemental form can increase the risk of atrial fibrillation, so Routhenstein cautions that your supplement use and dosage for omega 3’s is something to discuss with a healthcare professional. Those with known vitamin or mineral deficiencies: If a healthcare provider determines you have a vitamin or mineral deficiency that could impact your heart, then taking a supplement for that specific nutrient may be beneficial. This includes vitamins A, B6, folic acid, calcium, magnesium, and vitamins D, C, and E. Those with allergies or intolerances: If you have an allergy to foods like fish, you might consider an omega-3 supplement to ensure you get enough of these healthy fats for heart health—though you'd want to choose a vegan option. Our Picks In This Article Expand Our Top Picks for Cholesterol Our Top Picks for Blood Pressure Are Heart Health Supplements Beneficial? Our Picks Our Picks Who May Not Benefit From Heart Health Supplements How We Select Supplements What to Look For in Heart Health Supplements Our Experts Why Trust Verywell Health Best Omega-3 Nordic Naturals Ultimate Omega Softgels Amazon View On Amazon $23 View On Walmart $40 View On Riteaid.com $32 Pros Third-party tested Lemon flavored to avoid fishy aftertaste and burps Fish oil is sustainably sourced Cons It may interact with some medications Key specs Form: 2 soft gels | Dose: 1280 mg omega-3 | Third-Party Tested: Yes | Servings Per Container: 60 Why We Recommend It Omega-3 fats can potentially benefit the heart by lowering blood triglycerides and cholesterol, improving blood pressure, and reducing inflammation. Because of this, omega-3s may be considered a heart health supplement that can target many areas of heart health. Our top pick for an omega-3 supplement for heart health is Nordic Naturals Ultimate Omega. This fish oil supplement comes in soft gels, so it is easy to swallow. This supplement can provide the right amount of omega-3s to provide these heart health benefits for cholesterol and blood pressure. The two soft gel serving sizes provide 650 milligrams of EPA and 450 milligrams of DHA for a combined amount of 1280 milligrams. This is in line with the recommended intake of 0.5 to 1.8 grams of combined EPA and DHA per day. We like that this fish oil supplement is lemon-flavored, so you won’t experience that dreaded fishy aftertaste or burps. Plus, it is free from artificial fillers or additives and the fish are sustainability sourced. Nordic Naturals also provides a Certificate of Analysis for each product to verify that it has been third-party tested. Things To Consider If you are following a vegan or vegetarian diet, this product is not appropriate for you as the omega-3s are sourced from deep-sea fish. It can interfere with certain medications, like blood thinners, so if you take medications, always consult a healthcare professional before using them. Best Vegan Omega-3 Ritual Omega 3 DHA & EPA Amazon View On Amazon $37 View On Ritual.com Pros Traceable ingredients and third-party tested Citrus scented Omega-3 in EPA and DHA form from algae Cons May need to take several pills depending on your needs Key specs: Form: 1 soft gel | Dose: 500 mg | Third-Party Tested: Yes | Servings Per Container: 30 Why We Recommend It If you are a vegan, vegetarian, have a fish allergy, or simply do not enjoy eating fish, you might consider turning to a vegan omega-3 supplement like Ritual Omega 3 DHA-EPA to get a dose of these heart-healthy fats. This supplement includes about 500 milligrams total omega-3s from algae, with 308 milligrams of DHA per serving and 154 milligrams of EPA. This comes in soft gel form, with citrus essence for a pleasant flavor. It is third-party tested, and free of common food allergens, and Ritual uses traceable ingredients to ensure this product is free of harmful contaminants. Things To Consider Each capsule contains 500 mg of omega-3s, so if a higher dose is recommended for you, you may need to take multiple pills daily. Best Fiber Supplement Yerba Prima Psyllium Husks Powder Amazon View On Amazon $28 View On Walmart $28 View On IHerb $14 Pros Single-ingredient Budget-friendly It may help improve blood sugar management and bowel regularity Most researched-backed fiber supplement for heart health Cons Thickens quickly in liquids Key specs: Form: powder (5 grams, 1 teaspoon) | Dose: 4.5 g fiber | Third-Party Tested: Yes - the whole husk | Servings Per Container: 136 Why We Recommend It Dietary fiber, the non-digestible parts of plants, provides many health benefits. For example, soluble, non-fermentable, gel-forming fiber supplements like this psyllium husk can help lower LDL cholesterol levels and heart disease risk. Routhenstein also suggests eating foods high in soluble fiber—like lentils, barley, and chia seeds—can also help lower LDL cholesterol naturally. We like Yerba Prima Psyllium Husk Powder as a fiber supplement because it only contains ground psyllium husk. While this specific product is not third-party tested, their whole husk product is, and it passed for purity, potency, and potential contaminants like heavy metals. We chose the powdered form because it is a more concentrated fiber supplement and dissolves more easily in water compared to the whole husks. Plus, you can mix this powder into smoothies and oatmeal for convenience. In addition to the cholesterol-lowering benefits, psyllium husk can also help alleviate digestive issues such as diarrhea and constipation, improve bowel regularity, regulate blood sugar, and regulate appetite. To take this supplement, simply mix one teaspoon of powder into at least eight ounces of water, and then drink it immediately—psyllium husk thickens quickly in liquid. Things To Consider Make sure you are drinking enough water when supplementing with fiber to avoid gastrointestinal issues such as constipation and bloating. You should also be aware that fiber supplements can reduce the absorption of certain medications. If you are taking any medication, have difficulty swallowing, or have any active gastrointestinal inflammation or disease, you should consult a healthcare provider before taking a fiber supplement. Remember that fiber supplements are not meant to replace the fiber you get from foods but can be helpful if you struggle to reach the recommended daily fiber intake. Best Garlic Supplement Swanson Odor-Controlled Garlic Amazon View On Amazon $20 View On Walmart $14 Pros Odor-controlled to avoid garlicky-breath High amounts of allicin and SAC Third-party tested Cons May cause stomach discomfort for some Must be taken 3 times a day Key specs: Form: 1 capsule, 3 times per day | Dose: 500 mg per capsule | Third-Party Tested: Yes | Servings Per Container: 66 Why We Recommend It We recommend Swanson Odor-Controlled Garlic because it is in an easy capsule form. It contains 500 milligrams of allicin per serving, which is one of the active compounds in garlic, along with high amounts of S-allyl cysteine (SAC), an antioxidant found in garlic. While research is mixed, some studies suggest that if you have high levels of total and LDL cholesterol, then taking a garlic supplement may be helpful. More limited research suggests that garlic supplements may also be helpful for lowering high blood pressure. While this sounds promising, note that the beneficial effect of garlic is relatively small, and it may take over eight weeks to notice any changes. Things To Consider The recommended dose is one capsule three times per day with food or water, which may be inconvenient. Also, keep in mind that some people experience stomach upset with garlic supplements. Best Berberine Thorne Berberine 1,000 mg Amazon View On Amazon $40 View On Walmart $40 View On IHerb $38 Pros No artificial flavors Free of major food allergens Trusted brand with internal testing Cons Research not as strong Not third-party tested Key specs: Form: 2 capsules | Dose: 1000 mg | Third-Party Tested: No | Servings Per Container: 30 Why We Recommend It Berberine, a compound found in some plants, has been studied for its potential ability to help protect against high blood pressure and high cholesterol. Some research shows that berberine, when combined with lipid-lowering medications, may be more effective in lowering cholesterol levels than medications alone. While research is mixed, some studies also show that when combined with lifestyle changes, berberine can help lower high blood pressure, as well as improve blood sugar metabolism. However, keep in mind that more research is needed to confirm berberine’s role in heart health and what dose may be best. Thorne Berberine contains 1000 milligrams of berberine in each capsule, and the recommended dose is two capsules per day. Thorne’s high-quality products are free from artificial flavors, and this product is also soy and dairy-free. Thorne is a trusted brand with research-backed products that does several rounds of internal testing for identity, purity, and potency to make sure they are free of any contaminants. Things To Consider This product is not meant to replace any medications you use, and you should consult a healthcare professional before taking it, especially if you are taking blood cholesterol medication. It's recommended that you avoid this product if you are pregnant. Best Coenzyme Q10 GNC CoQ-10, 100 mg Amazon View On Amazon $22 View On Walmart $40 View On Riteaid.com $28 Pros ConsumerLab.com tested and approved Soft gel form Can vary dosage depending on your needs Cons No exact guidance from research on dosage requirements Key specs: Form: 1-4 soft gels | Dose: 100 mg | Third-Party Tested: Yes | Servings Per Container: 60 Why We Recommend It Coenzyme Q10 (CoQ10) is a nutrient our bodies produce that helps convert food into energy and acts like an antioxidant. It can help protect blood vessels and heart tissue from damage that is commonly associated with heart disease, and many people with heart disease have low levels of CoQ10. CoQ10 has also been shown to be helpful in treating congestive heart failure and high blood pressure. Some studies show that CoQ10 supplementation among people with heart failure may improve symptoms and decrease the risk of dying from heart issues. However, few studies have looked at the impact of CoQ10 on the prevention of heart disease, and the results are mixed. Note that you can get small amounts of CoQ10 in some foods, such as fatty fish, organ meats, and vegetables, but a larger dose can be obtained through supplementation. We recommend GNC CoQ-10 because it comes in soft gel form with 100 milligrams per soft gel. The recommended dose is one to four soft gels taken with food, as individual recommended doses can vary. CoQ10 is typically best absorbed when taken with fat-containing foods, so taking it with a meal can help ensure the best absorption. GNC CoQ-10 was tested in ConsumerLab.com’s voluntary Quality Certification Program and was a top pick in ConsumerLab.com’s 2022 CoQ10 Supplements Review. Things To Consider CoQ10 supplements may claim to benefit those taking statin drugs. The idea is that CoQ10 would improve myopathy, or weakened muscles caused by statin drugs, but more research is needed. If you take statins or other medications, you should consult a healthcare professional before taking CoQ10. CoQ10 can also interfere with sleep for some people. Also, note that this supplement contains gelatin, which isn’t suitable for a vegan or vegetarian diet. Best Magnesium Supplement Pure Encapsulations Magnesium (Glycinate) Amazon View On Amazon $45 View On Walmart $45 View On Pureformulas.com Pros Form is well-tolerated Free from major allergens Third-party tested Cons May require up to 4 capsules daily, depending on needs Key specs Form: 1 capsule | Dose: 120 mg | Third-Party Tested: Yes | Servings Per Container: 180 Why We Recommend It Magnesium is an electrolyte involved in blood pressure regulation, so getting enough magnesium is important for heart health. You can get magnesium from green leafy vegetables, legumes, nuts, and whole grains, but many people do not eat enough of these magnesium-rich foods. If you are deficient in magnesium or do not regularly eat foods high in magnesium, a healthcare provider may recommend a magnesium supplement. We recommend Pure Encapsulations Magnesium, as this supplement contains magnesium glycinate, which is typically a well-tolerated form of magnesium. Pure Encapsulations products are third-party tested and free from major allergens such as wheat, soy, dairy, eggs, nuts, and tree nuts. Each capsule provides 29% of the Daily Value of magnesium. Things To Consider You should be aware that very high magnesium intakes (well above the UL of 350 mg per day) can lead to irregular heartbeat and other negative symptoms. Magnesium supplements can also interfere with antibiotics, diuretics, and proton pump inhibitors. Best Folate Doctor’s Best Fully Active Folate Amazon View On Amazon $9 View On Walmart $14 View On Drbvitamins.com Pros Vegetarian and vegan-friendly Budget-friendly Third-party tested Provides 100% Daily Value of Folate Cons Larger capsule Key specs: Form: Capsule | Dose: 1 capsule daily | Third-Party Tested: Yes | Servings Per Container: 90 Why We Recommend It Folate, otherwise known as vitamin B9, can help break down the amino acid homocysteine. If you are not getting enough folate (or vitamin B12), you can develop high levels of homocysteine in the blood. This is important because high levels of homocysteine are associated with a higher risk of heart disease. Some studies have also found folic acid supplementation can lower stroke risk for those with heart disease, and high blood pressure is a main risk factor for stroke. Doctor’s Best Fully Active Folate stands out as a folate supplement because it has folate as methylfolate, which is a well-absorbed and active form meaning the body doesn’t need to alter it in order to use it. Some individuals with an MTHFR gene mutation cannot fully convert folate into its active form and need to take folate in the methylated form like in this supplement. This product is budget-friendly, third-party tested, and suitable for vegans. The recommended dose is one capsule per day, which provides 100% of the Daily Value of folate. Things To Consider If you are aware that you have a gene mutation known as MTHFR, we recommend speaking with a healthcare professional to determine the best supplement option for you. Best L-Arginine NOW Double Strength L-Arginine Amazon View On Amazon $17 View On Walmart Pros Easy to adjust the dose as needed Trusted brand with internal testing Vegan friendly Cons Larger tablet size The recommended dose may not be high enough to benefit blood pressure Key specs: Form: 2 tablets | Dose: 1000 mg per tablet | Third-Party Tested: No | Servings Per Container: 60 Why We Recommend It L-Arginine is an amino acid that is used by blood vessels to make nitric oxide (NO). Nitric oxide can help blood vessels relax, which can result in lower blood pressure. Therefore, supplementing with L-arginine may help lower blood pressure in people with high blood pressure. Note most of the benefit from lowering blood pressure is only seen in those with high blood pressure, not in people with normal blood pressure levels. Also, the effect of L-arginine on blood pressure is modest, up to 11 mmHg for systolic blood pressure. Now Double Strength L-Arginine has 1,000 mg per tablet. The amount you need to lower your blood pressure can vary, so we like that this dose can be tailored to your individual needs. Some research suggests a dose of four grams per day of L-arginine may be needed for blood pressure benefits, but more research is needed. Things to Consider It is recommended that you take this L-arginine in between meals or before bedtime. If you only take one or two tablets per day, it may not be enough to notice an effect on blood pressure, as more research is needed on the optimal dose. Who May Not Benefit From Heart Health Supplements Supplements for heart health are not always necessary. There are certain groups who may not benefit from heart health supplements: Those without heart conditions: If you are healthy and are not at increased risk of heart disease, then supplements may not be necessary. We recommend focusing on lifestyle behaviors that support overall heart health before adding a supplement.Those eating a balanced diet: If you eat a balanced diet and are not deficient in any vitamins or minerals that are related to heart health, such as fiber, magnesium, and omega-3 fats, then taking a vitamin or mineral supplement may not be needed.Those taking certain medications: If you are taking any medications, you should consult with a healthcare provider before using heart health supplements. Routhenstein says, “Certain supplements [should not be taken] with certain medications, which is why it is so important to consult with your health care team first, including your registered dietitian. For instance, fish oil may sound heart healthy, but if you are on a blood clotting/thinning medication, your risk of bleeding excessively increases.” How We Select Supplements Our team works hard to be transparent about why we recommend certain supplements; you can read more about our dietary supplement methodology here. We support supplements that are evidence-based and rooted in science. We value certain product attributes that we find to be associated with the highest quality products. We prioritize products that are third-party tested and certified by one of three independent third-party certifiers: USP, NSF, or ConsumerLab.com. It's important to note that the FDA does not review dietary supplements for safety and effectiveness before they go to market. Our team of experts has created a detailed, science-backed methodology to choose the supplements we recommend. What to Look For in Heart Health Supplements Third-Party Testing Supplements that are third-party tested are sent to a lab where they are tested to ensure they contain what they say they contain and are not contaminated with specific high-risk, common contaminants. However, it’s important to note: Third-party testing does not test to see if a product is effective or safe for everyone, and it does not ensure the supplement will not interact with other supplements or medications. Not all third-party testing is created equal. It is not uncommon for supplement companies to pay labs for certificates after conducting minimal to no testing. The third-party certifications we can trust are: ConsumerLab.com, NSF, and USP. However, these certifications are difficult to obtain and/or expensive for manufacturers, so many companies choose not to get their products tested by one of these three organizations. Sometimes products tested by these three companies are more expensive to try to offset the cost they pay for certification. Just because a supplement is not tested by one of these three companies, it does not mean it’s a bad product. We recommend doing some research on the reputability of the manufacturer and calling up the manufacturer and their testing lab to determine their protocols and decide if you feel comfortable consuming the supplement. Supplements always risk contamination, so it is important to choose those that have been third-party tested when possible. Fiber supplements can be contaminated with heavy metals, and fish oil supplements can go rancid, which means the beneficial effects go down. This can result in an unpleasant taste and can reduce safety and efficacy. In addition to opting for a supplement that has been third-party tested, always follow the manufacturer’s tips for storage and expiration date. If a supplement is not third-party tested, strong in-house testing and traceable ingredients are important to look for. Form Supplements for heart health come in many forms, including pills, capsules, soft gels, and liquids. Certain supplements may contain added ingredients such as B vitamins, vitamin C, or stabilizers. It is best to check labels to be certain that you know what a supplement contains and to make sure there aren't ingredients that may not benefit you. Ingredients & Potential Interactions It is essential to carefully read the ingredient list and nutrition facts panel of a supplement to know which ingredients and how much of each ingredient is included relative to the recommended daily value of that ingredient. Please bring the supplement label to a healthcare provider to review the different ingredients contained in the supplement and any potential interactions between these ingredients and other supplements and medications you are taking. Be sure to check supplement labels to see what ingredients may be present. Medication Interactions: Certain supplements should be avoided or taken with caution if you are using particular medications. If you take blood thinning medication or medication that lowers blood pressure, please discuss taking any supplement with a healthcare provider. Fiber supplements may interact with diabetes medications and interfere with your body’s ability to absorb certain medications, such as tricyclic antidepressants, carbamazepine, digoxin, lithium, or diabetes medications. Folate and magnesium can also interact with certain medications. If you are taking medications, consult with a healthcare provider before using supplements for heart health. Added Ingredients: Supplements may contain added ingredients such as vitamins, minerals, caffeine, or herbs. When possible, it’s best to choose supplements without these added ingredients, especially if you have any medical conditions or take other medications. How Much is Too Much? Routhenstein says, “It is important to assess the dosages of all supplements; many people think that more is better, and that simply is not true. Having mega-doses of certain nutrients in supplemental form can lead to toxicity, cardiac arrhythmias, GI distress, and kidney and liver damage.” You should always review dosing with a healthcare provider. For example, taking high doses of folate can mask a vitamin B12 deficiency, while taking high doses of magnesium can lead to GI upset, nausea, irregular heartbeat, and cardiac arrest. Taking too much fiber could lead to gas and bloating. It is important to avoid exceeding nutrient upper limits established by the National Institutes of Health Office of Dietary Supplements. Our Experts We consulted experts at every stage of researching and reporting this story, from building a baseline of supplements to researching potential interactions. Here are some of the people we consulted: Michelle Routhenstein, MS RD CDE CDN, a Registered Dietitian specializing in heart health who works with patients to help manage and prevent heart disease and heart attacks. Shushy Rita Setrakian, MS, RD, a Registered Dietitian and one of our nutrition and supplement commerce editors. Shushy is passionate about converting nutrition science into meaningful dietary recommendations. Why Trust Verywell Health Tamar Kane, MS, RD is a registered dietitian and marathon runner. Tamar has her master's degree in nutrition and exercise physiology from Teachers College, Columbia University. She specializes in working with plant-based athletes, one of the populations at highest risk for iron deficiency. 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Effect of l-arginine supplementation on blood pressure in adults: a systematic review and dose-response meta-analysis of randomized clinical trials. Adv Nutr. 2022;13(4):1226-1242. doi:10.1093/advances/nmab155 Mount Sinai Health System. Fiber. By Tamar Kane, MS, RD Tamar is a former combat fitness instructor in the Israel Defense Forces.Tamar is a Registered Dietitian-Nutritionist with Master's in Nutrition and Exercise Physiology.Tamar is the founder of Tamar Kane Nutrition, a nutrition practice that supports athletes. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit