Brain & Nervous System Multiple Sclerosis Symptoms What’s the Link Between MS and Brain Fog? By Ashley Olivine, Ph.D., MPH Published on October 07, 2022 Medically reviewed by Nicholas R. Metrus, MD Print Table of Contents View All Table of Contents What Is Brain Fog? Brain Fog & MS How to Deal With It Frequently Asked Questions Multiple sclerosis (MS) is an autoimmune disease that attacks healthy cells in the brain and spinal cord. There are many symptoms of MS, one of which is brain fog - difficulty with memory, concentration, and brain function. Learn more about MS brain fog, including what causes it, how to deal with it, and more. Tinpixels / Getty Images What Is Brain Fog? Brain fog, sometimes called cog fog, is a term that describes some of the cognitive symptoms of MS and other medical conditions that affect brain function. Symptoms of brain fog may include difficulties related to thinking and brain function, such as: Confusion and decision making Memory, attention, and concentration Understanding, processing, and thought delays Planning and disorganization Cognitive symptoms affect roughly 45% to 60% of people with MS. What Causes Brain Fog in Multiple Sclerosis? Brain fog can be a symptom of MS for several reasons. Lesions MS can cause lesions (spots or scars that show damaged cells) in the brain that can affect cognitive abilities and cause brain fog. These spots can be seen on magnetic resonance imaging, or MRI images, and are used to help diagnose MS. Areas of the Brain Affected The brain consists of white matter and gray matter, and both play a vital role in overall body function: Gray matter is the outermost layer of the brain and helps with the processing required for daily functioning. White matter is farther from the surface and serves as a link between gray matter and the rest of the body; it sends messages and communicates with the rest of your body. Myelin is a coating that protects the nerves in the brain and spinal cord, and speeds up the messaging from your brain to other body parts, and gives the white matter its white hue. MS occurs when the immune system attacks myelin, causing it to deteriorate. The damage to the brain caused by MS tends to primarily affect the white matter since it has more myelin, but the gray matter can also be affected. Damage to different brain areas can lead to cognitive symptoms such as confusion and memory challenges that people call brain fog. Nerve Definition Nerves are cells that are responsible for communicating between the brain and other parts of the body. The Anatomy of the Brain How to Deal With It The cognitive symptoms of MS can be challenging and severe enough to impact daily life and functioning. However, there are things people with MS brain fog can do to minimize symptoms and prevent it from negatively impacting life. How Multiple Sclerosis Is Treated Tips for living with MS brain fog include: Talk about it. Discuss your cognitive symptoms and brain fog with your healthcare provider so they can help. These challenges are effects of MS, just like the physical symptoms. Learn about it. There are resources available specifically for MS-related cognitive challenges, including research and educational material. Knowing more about MS can lead to finding solutions that can help. Support mental and emotional health. Mental and emotional challenges such as stress, depression, and anxiety can worsen cognitive symptoms. Finding support and treatment for mental and emotional difficulties can help you cope. Lean on family and friends. It can help to have friends and family members come with you to appointments and help manage daily tasks, such as reminding you to take medications. Use tools and processes. Alarms, apps, and planners can help you stay on track with organization and reminders to ensure you follow your treatment plan. Lifestyle Changes In addition to general coping strategies for MS brain fog, some lifestyle changes can help. Diet. No specific diet plan is recommended for MS, but research has shown that focusing on vegetables and fruits and not overeating can help. Additionally, omega-3 fatty acids, found in foods like flax seeds, chia seeds, walnuts, and avocados, have been shown to help. Exercise. Regular exercise, three times per week, has been shown to improve cognitive function in people with MS. Intellectual enrichment. Brain exercises, such as puzzles, crafts, or activities, can challenge the brain and keep it nimble. While this may not reverse cognitive decline, it has been shown to prevent or slow future decline in people with MS. Summary Multiple sclerosis, or MS, is a lifelong disease that happens when the immune system attacks healthy cells in the brain and spinal cord. Brain fog, also called cog fog or cognitive decline, is a group of symptoms related to brain function. This may include memory loss, confusion, slowed thinking, and more. Brain fog may occur as a symptom of MS due to damage to the myelin in the brain. This damage can be seen as lesions on MRI scans. People with MS can cope with brain fog and prevent it from worsening by eating a healthy diet with omega-3-rich foods, exercising regularly, seeking support, and using alarms and planners to stay on track with treatment. A Word From Verywell Experiencing brain fog and other symptoms of MS can be challenging and life-changing. Help is available, and there are ways to cope. If you or someone you know is experiencing brain fog associated with MS, reach out to a healthcare professional, such as a primary care healthcare provider or neurologist, for support. Frequently Asked Questions Do autoimmune diseases cause brain fog? Brain fog is a symptom of many autoimmune diseases, including MS. The link between autoimmune diseases and brain fog is not entirely understood, but some research points to inflammation, or swelling, playing a role. Does brain fog in MS go away? No, MS brain fog does not go away. It often stays the same or may worsen over time. However, it may come and go, and there are things people with MS can do to improve brain function or prevent it from getting worse. Do brain MRIs detect multiple sclerosis lesions? MRIs of the brain can detect lesions caused by multiple sclerosis and help to diagnose MS. However, no test is perfect, and an MRI can miss them. What cognitive symptoms do people with MS have? People with MS may experience cognitive symptoms such as difficulty with memory, concentration, decision-making, and thinking. 12 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Johns Hopkins Medicine. Multiple sclerosis (ms). Multiple Sclerosis Trust. Thinking and memory problems. Guimarães J, Sá MJ. Cognitive dysfunction in multiple sclerosis. Front Neurol. 2012. doi:10.3389/fneur.2012.00074 National Institutes of Health. A cellular map of brain lesions in multiple sclerosis. National Institutes of Health. Neuroanatomy, gray matter. National Multiple Sclerosis Society. What is myelin? Lassmann H. Multiple sclerosis pathology. Cold Spring Harb Perspect Med. 2018;8(3):a028936. doi:10.1101/cshperspect.a028936 National Multiple Sclerosis Society. Managing cognitive problems in MS. 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Brain. 2010;133(2):362-374. doi:10.1093/brain/awp307 By Ashley Olivine, Ph.D., MPH Dr. Olivine is a Texas-based psychologist with over a decade of experience serving clients in the clinical setting and private practice. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit